Extra cytoplasmic function σ factor activation
نویسندگان
چکیده
منابع مشابه
The extra cytoplasmic function sigma factor sigma(E) is essential for Mycobacterium tuberculosis virulence in mice.
The virulence of a Mycobacterium tuberculosis H37Rv sigE mutant was studied in immunodeficient and immunocompetent mice. The mutant was strongly attenuated in both animal models and induced formation of granulomas with different characteristics than those induced by the wild-type strain.
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F is established, F (encoded by the SpoIIAC gene) is the first factor to establish forespore-specific gene expression by inducing expression of other sporulation-specific factors, which in turn direct the expression of downstream genes necessary for spore development SpoIIAB is also a Cell type-specific transcription during Bacillus sporu-lation is established by F. SpoIIAB is an anti-...
متن کاملChapter 1 General Introduction Figure 2. Activation of the E. Coli Ecf Sigma Factor Σ Activation of Stress Responsive (rpoe-like) Σ Activation of Iron Starvation (feci-like) Σ
70 family of sigma factors. Regulation of gene expression is an essential mechanism that allows bacteria to rapidly adapt to alterations in their environment. In this way, they preserve energy and profit by expressing particular genes only when required. Gene expression in bacteria is regulated primarily at the level of transcription initiation by modulating promoter recognition of the RNA poly...
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σ factors endow RNA polymerase with promoter specificity in bacteria. Extra-Cytoplasmic Function (ECF) σ factors represent the largest and most diverse family of σ factors. Most ECF σ factors must be activated in response to an external signal. One mechanism of activation is the stepwise proteolytic destruction of an anti-σ factor via Regulated Intramembrane Proteolysis (RIP). In most cases, th...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2012
ISSN: 1369-5274
DOI: 10.1016/j.mib.2012.01.001